Dependency Map Complexes

Integrating protein structure predictions and genetic dependencies in cancer to identify functional multi-protein complexes.

This resource can be explored via a summary table or cluster maps that represent functional groupings or disease associations

 

Described in the manuscript: Integrating computational protein structure predictions and genetic dependencies yields an atlas of human multi-protein complexes (DepCom)

Original functional data from DepMap

Data on binary structure predictions from the Human Interactome

Related resource: AlphaBridge